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J Invest Dermatol. 2013 Jan;133(1):7-9. doi: 10.1038/jid.2012.446.

Tuning Wnt signals for more or fewer hairs.

Author information

1
Department of Pathology, University of Southern California, Los Angeles, CA, USA.

Abstract

Activation of β-catenin was shown to be of central importance for hair development and cycling. Recent progress brought more understanding to how Wnt signaling is regulated during hair follicle generation and regeneration, telogen-anagen reentry, and extra-follicular macro-environmental modulation. This new understanding presents multiple possibilities to fine tune Wnt signaling for desired hair growth.

PMID:
23299447
PMCID:
PMC3686512
DOI:
10.1038/jid.2012.446
[Indexed for MEDLINE]
Free PMC Article

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