Format

Send to

Choose Destination
See comment in PubMed Commons below
Pediatrics. 2013 Feb;131(2):e626-8. doi: 10.1542/peds.2012-0587. Epub 2013 Jan 6.

Oral sildenafil as a rescue therapy in presumed acute pulmonary hypertensive crisis.

Author information

1
BMBS, Paediatric Intensive Care Unit, Nottingham Children's Hospital, Queen's Medical Centre, Derby Rd, Nottingham, NG7 2UH United Kingdom. andrewmaxted@nhs.net

Abstract

A 23-week-old baby, born at 26(+2) weeks, presented to the hospital with critical respiratory failure, which was impossible to stabilize. She had unstable oxygen saturations between 35% and 95%. A presumptive diagnosis of bronchopulmonary dysplasia with associated pulmonary hypertensive crisis was made. In the absence of inhaled nitric oxide, 2 oral doses of 1 mg/kg sildenafil were given, with a dramatic improvement 30 to 45 minutes later. Her oxygenation index fell from 43 to 14. She made a full recovery and was discharged from the hospital 2 weeks later.

PMID:
23296435
DOI:
10.1542/peds.2012-0587
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center