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Jpn J Clin Oncol. 2013 Mar;43(3):314-7. doi: 10.1093/jjco/hys229. Epub 2013 Jan 4.

The first case of omental metastasis from primary choroidal melanoma.

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  • 1Department of Medical Oncology, The Third Affiliated Hospital of Harbin Medical University, 150 Haping Rd, Nangang District, Harbin, China.


Choroidal melanoma is the most common intraocular malignancy and can be fatal in half of the patients because of metastatic disease. Metastasis of choroidal melanoma to the omentum is extremely rare and, to our knowledge, no such case has ever been described in the literature. Here we present a 41-year-old Chinese man with an omental metastasis, 5 years after he was diagnosed with a spindle-cell-type malignant melanoma of the choroid and had his left eye enucleated. The patient demonstrated some uncommon symptoms, but the diagnosis was confirmed histopathologically. The cells were positive for S-100, HMB-45 and Melan-A proteins. He underwent a complete tumor resection and concomitantly received chemotherapy, biological treatment and traditional Chinese medicine. At 2-year follow-up, this patient continues to do well.

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