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Molecules. 2013 Jan 4;18(1):690-700. doi: 10.3390/molecules18010690.

Antioxidant action and therapeutic efficacy of Allium sativum L.

Author information

1
Department of Pharmacy, University of Salerno, Via Ponte don Melillo, Fisciano, Salerno 84084, Italy. annacap@unisa.it

Abstract

Allium sativum (L.) is rich in antioxidants which help destroy free radicals particles that can damage cell membranes and DNA, and may contribute to the aging process as well as the development of a number of conditions, including heart disease and cancer. Antioxidants neutralize free radicals and may reduce or even help prevent some of the damage they cause over time. The antioxidant activity of fresh Allium sativum L. (garlic) is well known and is mainly due to unstable and irritating organosulphur compounds. Fresh garlic extracted over a prolonged period (up to 20 months) produces odourless aged garlic extract (AGE) containing stable and water soluble organosulphur compounds that prevent oxidative damage by scavenging free radicals. The aim of this review was to understand the mechanism of antioxidant action and therapeutic efficacy of garlic.

PMID:
23292331
PMCID:
PMC6269925
DOI:
10.3390/molecules18010690
[Indexed for MEDLINE]
Free PMC Article

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