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Intern Med. 2013;52(1):85-8. Epub 2013 Jan 1.

Thyrotoxic periodic paralysis with Graves' disease leading to the discovery of a hidden nonclassic 11β hydroxylase deficiency.

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1
Department of Endocrinology and Metabolism, Chosun University Hospital, Republic of Korea.

Abstract

11β hydroxylase deficiency (OHD) is one of the main causes of congenital adrenal hyperplasia. There have been only a few reported cases of nonclassic 11β OHD, a milder form of the disease. It is difficult to detect occult nonclassic 11β OHD because patients present with no or mild symptoms. We herein present a case of thyrotoxic periodic paralysis (TPP) with Graves' disease leading to the discovery of a hidden nonclassic 11β OHD. In this case, increased levels of thyroid hormone seem to have induced symptoms of occult nonclassic 11β OHD and aggravated TPP.

PMID:
23291679
[Indexed for MEDLINE]
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