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J Am Vet Med Assoc. 1990 Apr 1;196(7):1073-6.

Naltrexone for treatment of acral lick dermatitis in dogs.

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Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80526.


Acral lick dermatitis (lick granuloma) was diagnosed in 11 dogs on the basis of history, physical examination, and histopathologic findings. A predilection for the left forelimb was noticed. All 11 dogs were given the narcotic antagonist naltrexone. Successful treatment (cessation of licking, reepithelialization of lesions) was seen in 7 dogs. All 7 dogs' lesions recurred when naltrexone was stopped, but reepithelialized in 5 dogs when the drug was readministered. Adverse effects (drowsiness, withdrawal from owner) were seen in 1 dog, but resolved within 48 hours of stopping the drug.

[Indexed for MEDLINE]

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