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J Bras Pneumol. 2012 Nov-Dec;38(6):700-7.

Reference values for sniff nasal inspiratory pressure in healthy subjects in Brazil: a multicenter study.

[Article in English, Portuguese]

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Rede Nordeste de Biotecnologia – RENORBIO, Northeastern Biotechnology Network – Natal, Brazil.



The objectives of this study were to determine reference values for sniff nasal inspiratory pressure (SNIP) and to propose reference equations for the population of Brazil.


We evaluated 243 healthy individuals (111 males and 132 females), between 20 and 80 years of age, with an FVC and FEV1/FVC ratio > 80% and > 85% of the predicted value, respectively. All of the subjects underwent respiratory muscle strength tests to determine MIP, MEP, and SNIP.


We found that SNIP values were higher in males than in females (p < 0.05) and that SNIP correlated negatively with age, for males (r = -0.29; p < 0.001) and for females (r = -0.33; p < 0.0001). Linear regression also revealed that age influenced the predicted SNIP, for males (R² = 0.09) and females (R² = 0.10). We obtained predicted SNIP values that were higher than those obtained for other populations.


We have devised predictive equations for SNIP to be used in adults (20-80 years of age) in Brazil. These equations could help minimize diagnostic discrepancies among individuals.

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