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Gynecol Obstet Fertil. 2013 Jan;41(1):27-30. doi: 10.1016/j.gyobfe.2012.11.003. Epub 2012 Dec 31.

[Impact of polycystic ovary syndrome on oocyte and embryo quality].

[Article in French]

Author information

1
Service d'histologie-embryologie-cytogénétique-CECOS, hôpital Jean-Verdier, AP-HP, avenue du 14-Juillet, Bondy, France. nathalie.sermondade@jvr.aphp.fr

Abstract

This review analyzes the literature concerning oocyte and embryo quality, in case of in vitro fertilization (IVF) for women with polycystic ovary syndrome (PCOS). Alterations in oocyte quality, and consequently in embryo quality, may be due to endocrine and intra-ovarian paracrine changes. However, most of publications find similar biological and clinical results after IVF, with or without microinjection, for women with PCOS compared to those obtained in control populations. Subgroups of more pejorative outcome probably exist within PCOS population. Finally, obesity, which is frequent in PCOS, is clearly deleterious, and multidisciplinary care, including lifestyle modifications, is then needed.

PMID:
23286960
DOI:
10.1016/j.gyobfe.2012.11.003
[Indexed for MEDLINE]

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