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World Allergy Organ J. 2009 Jul;2(7):128-9. doi: 10.1097/WOX.0b013e3181abe7b6.

Chronic human herpes virus 8 infection successfully treated with valganciclovir.

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From the 1Campbelltown Hospital, Sydney South West Area Health Service, Campbelltown NSW, Australia; 2University of Western Sydney, Sydney NSW, Australia; and 3St Vincent's Hospital, Department of Dermatology, University of New South Wales, Sydney, Australia.



: A 57 year old Italian female with a 3 year history of constituitional symptoms with non-HIV Kaposi sarcoma was referred to the immunology clinic. She was previously diagnosed with chronic human herpes virus 8 (HHV8) infection with positive HHV8 polymerase chain reaction in serum.


: Is valganciclovir effective in treating chronic human herpes virus 8 infection without Multicentric Castleman's Disease (MCD)?


: She was started on valganciclovir, resulting in remission of her symptoms, improvement in inflammatory markers and clearing of detectable HHV8 viraemia


: Valganciclovir is effective in treating symptomatic HHV8 infections without MCD.

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