Format

Send to

Choose Destination
See comment in PubMed Commons below
Allergy Asthma Immunol Res. 2013 Jan;5(1):3-15. doi: 10.4168/aair.2013.5.1.3. Epub 2012 Nov 28.

Oral immunotherapy for food allergy: towards a new horizon.

Author information

1
Division of Immunology and Allergy, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Abstract

Food allergy has increased dramatically in prevalence over the past decade in westernized countries, and is now a major public health problem. Unfortunately for patients with food allergy, there is no effective therapy beyond food allergen avoidance, and rapid medical treatment for accidental exposures. Recently, oral immunotherapy (OIT) has been investigated as a treatment for this problem. In this review, we will discuss the progress in developing OIT for food allergy, including a novel approach utilizing Xolair (anti-IgE monoclonal antibody, omalizumab) in combination with OIT. This combination may enhance both the safety and efficacy of oral immunotherapy, and could lead to a widely available and safe therapy for food allergy.

KEYWORDS:

Oral immunotherapy; anti-IgE; desensitization; food allergy; omalizumab; xolair

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease Icon for PubMed Central
    Loading ...
    Support Center