Format

Send to

Choose Destination
Front Biosci (Landmark Ed). 2013 Jan 1;18:366-70.

Prevalence and risk factor for MDR-GNB infection in liver transplantation.

Author information

1
Department of General Surgery, Shanghai First People Hospital, Medical School of Shanghai Jiaotong University, 85 Wu Jing Road, 200080, Shanghai, People's Republic of China. zhonglin_2012@yeah.net

Abstract

Liver transplantation (LT) has emerged as a viable therapy for various end-stage liver diseases. Multi-drug resistant Gram-negative bacilli (MDR-GNB) have emerged as predominant pathogens. The prevalence of MDR-GNB infection has been increasing in LT recipients, especially in early post-LT stages. MDR-GNB infection has become a main cause of death following LT. Since key elements of MDR-GNB infection after LT mainly include the pre-LT severity of underlying disease, technical problems, acute rejection, and so on, appropriate measures, such as improvement of LT technology and management, restriction of antibiotic use and immunosuppressive therapy advancement, should be commenced to prevent and control the occurrence of MDR-GNB infection. A better understanding of the prevalence of and risk factors for MDR-GNB infection complications is needed to improve quality of life and survival rate after LT.

PMID:
23276929
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Frontiers in Bioscience
Loading ...
Support Center