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Front Biosci (Landmark Ed). 2013 Jan 1;18:241-78.

The power of yeast to model diseases of the powerhouse of the cell.

Author information

1
Dept. of Physiology, Johns Hopkins School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205-2185, USA.

Abstract

Mitochondria participate in a variety of cellular functions. As such, mitochondrial diseases exhibit numerous clinical phenotypes. Because mitochondrial functions are highly conserved between humans and Saccharomyces cerevisiae, yeast are an excellent model to study mitochondrial disease, providing insight into both physiological and pathophysiological processes.

PMID:
23276920
PMCID:
PMC3874933
[Indexed for MEDLINE]
Free PMC Article

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