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Psychiatry Res. 2013 Apr 30;206(2-3):318-20. doi: 10.1016/j.psychres.2012.11.008. Epub 2012 Dec 29.

A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.

Author information

1
VA Mid-Atlantic Mental Illness, Research and Clinical Center, Durham, NC, USA.

Abstract

Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk for suicidality, depression, and functional impairment. We thus conducted a small (N=12) pilot randomized controlled trial (RCT) with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era veterans. Hospital Anxiety and Depression Scale (HADS) scores improved by 30.4% in the paroxetine group. Paroxetine may have promise for subthreshold PTSD.

PMID:
23276723
PMCID:
PMC3788578
DOI:
10.1016/j.psychres.2012.11.008
[Indexed for MEDLINE]
Free PMC Article

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