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Case Rep Neurol. 2012 Sep;4(3):236-9. doi: 10.1159/000346003. Epub 2012 Dec 12.

Familial transient global amnesia.

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Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK.


Following an episode of typical transient global amnesia (TGA), a female patient reported similar clinical attacks in 2 maternal aunts. Prior reports of familial TGA are few, and no previous account of affected relatives more distant than siblings or parents was discovered in a literature survey. The aetiology of familial TGA is unknown. A pathophysiological mechanism akin to that in migraine attacks, comorbidity reported in a number of the examples of familial TGA, is one possibility. The study of familial TGA cases might facilitate the understanding of TGA aetiology.


Familial occurrence; Migraine; Transient global amnesia

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