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Curr Opin Neurobiol. 2013 Apr;23(2):229-38. doi: 10.1016/j.conb.2012.11.012. Epub 2012 Dec 22.

Updating dopamine reward signals.

Author information

1
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK. ws234@cam.ac.uk

Abstract

Recent work has advanced our knowledge of phasic dopamine reward prediction error signals. The error signal is bidirectional, reflects well the higher order prediction error described by temporal difference learning models, is compatible with model-free and model-based reinforcement learning, reports the subjective rather than physical reward value during temporal discounting and reflects subjective stimulus perception rather than physical stimulus aspects. Dopamine activations are primarily driven by reward, and to some extent risk, whereas punishment and salience have only limited activating effects when appropriate controls are respected. The signal is homogeneous in terms of time course but heterogeneous in many other aspects. It is essential for synaptic plasticity and a range of behavioural learning situations.

PMID:
23267662
PMCID:
PMC3866681
DOI:
10.1016/j.conb.2012.11.012
[Indexed for MEDLINE]
Free PMC Article

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