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Int Arch Allergy Immunol. 2013;161(1):1-10. doi: 10.1159/000343018. Epub 2012 Dec 13.

Pooling birth cohorts in allergy and asthma: European Union-funded initiatives - a MeDALL, CHICOS, ENRIECO, and GA²LEN joint paper.

Collaborators (184)

Bousquet J, Anto JM, Akdis M, Auffray C, Keil T, Postma DS, Valenta R, Haahtela T, Cambon-Thomsen A, Lambrecht BN, Sunyer J, Akdis CA, Annesi-Maesano I, Arno A, Bachert C, Ballester F, Basagana X, Baumgartner U, Bindslev-Jensen C, Brunekreef B, Carlsen KH, Chatzi L, Eller E, Forastiere F, Garcia-Aymerich J, Guerra S, Gehring U, Hammad H, Heinrich J, Hohmann C, Kauffmann F, Kerkhof M, Kogevinas M, Koppelman GH, Kowalski ML, Kull I, Lau S, Lodrup-Carlsen KC, Lupinek C, Maier D, Makela MJ, Martinez FD, Momas I, Nawijn MC, Neubauer A, Oddie S, Palkonen S, Reitamo S, Rial-Sebbag E, Salapatas M, Siroux V, Smagghe D, Smit HA, Torrent M, Toskala E, van Oosterhout AJ, Varaso R, von Hertzen L, Wickman M, Wijmenga C, Wright J, Vrijheid M, Chatzi L, Duijts L, Jaddoe V, Kogevinas M, Lawlor D, Lucas P, Magnus P, Merletti F, Nieuwenhuijsen M, Nybo Andersen AM, Raat H, Stoltenberg C, Sunyer J, Nieuwenhuijsen M, Vrijheid M, Casas M, Bergström A, Carmichael A, Chen C-, Cordier S, Eggesbø M, Eller E, Fantini MP, Fernández MF, Fernández-Somoano A, Gehring U, Grazuleviciene R, Heinrich J, Hohmann C, Karvonen AM, Keil T, Kogevinas M, Koppen G, Krämer U, Kuehni CE, Magnus P, Majewska R, Nybo Andersen AM, Patelarou E, Petersen M, Pierik FH, Polanska K, Porta D, Richiardi L, Santos AC, Slama R, Sram RJ, Thijs C, Tischer C, Toft G, Trnovec T, Vandentorren S, Vardavas C, Vrijkotte TG, Wilhelm M, Wright J, Zuberbier T, Bousquet J, Burney PG, Van Cauwenberge P, Akdis CA, Bindslev-Jensen C, Bonini S, Fokkens WJ, Kauffmann F, Keil T, Kowalski ML, Kramer U, Kull I, Lau S, Lodrup-Carlsen K, Mullol J, Nizankowska-Mogilnicka E, Papadopoulos N, Toskala E, Wickman M, Anto J, Alm B, Alm J, Arshad SH, Bachert C, Bousquet PJ, Bravi F, Brunekreef B, Canonica GW, Carlsen KH, Custovic A, Dubakiene R, Eller E, Fantini MP, Forastiere F, Gjomarkaj M, Halken S, Host A, Heinrich J, Howarth P, Kuehni C, Lotvall J, Momas I, Mommers M, Porta D, Radon K, Ring J, Roberts G, Salapatas M, Schünemann HJ, Simpson A, Smit HA, Sunyer J, Szczecklik A, Thijs C, Todo-Bom A, Torrent M, Valenta R, Valovirta E, van Steen K, Von Berg A, von Mutius E, Wahn U, Wennergren G, Wijga AH, Zock JP.

Author information

1
University Hospital, Hôpital Arnaud de Villeneuve, Montpellier, France. jean.bousquet@inserm.fr

Abstract

Long-term birth cohort studies are essential to understanding the life course and childhood predictors of allergy and the complex interplay between genes and the environment (including lifestyle and socioeconomic determinants). Over 100 cohorts focusing on asthma and allergy have been initiated in the world over the past 30 years. Since 2004, several research initiatives funded under the EU Framework Program for Research and Technological Development FP6-FP7 have attempted to identify, compare, and evaluate pooling data from existing European birth cohorts (GA(2)LEN: Global Allergy and European Network, FP6; ENRIECO: Environmental Health Risks in European Birth Cohorts, FP7; CHICOS: Developing a Child Cohort Research Strategy for Europe, FP7; MeDALL: Mechanisms of the Development of ALLergy, FP7). However, there is a general lack of knowledge about these initiatives and their potentials. The aim of this paper is to review current and past EU-funded projects in order to make a summary of their goals and achievements and to suggest future research needs of these European birth cohort networks.

PMID:
23258290
DOI:
10.1159/000343018
[Indexed for MEDLINE]
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