Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Cancer Res. 2013 Feb 1;19(3):517-23. doi: 10.1158/1078-0432.CCR-12-1452. Epub 2012 Dec 17.

New strategies in prostate cancer: translating genomics into the clinic.

Author information

1
Weill Cornell Cancer Center Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

Abstract

With the rapidly developing use of next-generation sequencing technologies, there has been a surge in our knowledge of the genomic landscape of prostate cancer and a movement toward developing a molecular subclassification system for the disease. With this new understanding comes great clinical potential, both for the development of biomarkers as well as new therapeutic targets. Herein, we highlight the potential clinical use of recent discoveries and how they fit into our current paradigm. We describe the challenges that lie ahead as we move from genomic sequencing toward routine clinical practice and adopt precision cancer care for patients with prostate cancer.

PMID:
23248095
PMCID:
PMC4123124
DOI:
10.1158/1078-0432.CCR-12-1452
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center