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Mol Cell. 2012 Dec 14;48(5):663-4. doi: 10.1016/j.molcel.2012.11.024.

How infidelity creates a sticky situation.

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1
Department of Biochemistry & Molecular Biology, University of Chicago, Chicago, IL 60637, USA. dadrummond@uchicago.edu

Abstract

Errors in translation cause cytotoxic protein misfolding and aggregation. In this issue, Ling et al. (2012) show that scavenging or suppression of reactive oxygen species in E. coli reduces the cellular costs of error-induced aggregation.

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