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Elife. 2012 Dec 13;1:e00347. doi: 10.7554/eLife.00347.

Sliding to the rescue of damaged DNA.

Author information

1
is at the Department of Biochemistry and Molecular Biophysics, and the Howard Hughes Medical Institute , Columbia University , New York , United States bg2390@columbia.edu.

Abstract

Single-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired.

KEYWORDS:

DNA repair; E. coli; FRET; Homologous Recombination; Single Molecule

PMID:
23240090
PMCID:
PMC3510475
DOI:
10.7554/eLife.00347
[Indexed for MEDLINE]
Free PMC Article

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