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Surg Neurol Int. 2012;3(Suppl 4):S320-7. doi: 10.4103/2152-7806.103029. Epub 2012 Oct 31.

The role of intraoperative magnetic resonance imaging in glioma surgery.

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  • 1Department of Neurological Surgery, Hofstra North Shore-LIJ School of Medicine, Manhasset, New York, USA.

Abstract

For patients with gliomas, the goal of surgery is to maximize the extent of tumor resection while avoiding injury to functional tissue. The hope is to improve patients' survival and maintain the highest quality of life as possible. However, because of the infiltrative nature of gliomas these two goals often oppose each other so a compromise must be met. Many tools have been developed to help with this challenge of glioma surgery. Over the past two decades, intraoperative-magnetic resonance imaging (iMRI) has emerged as an increasingly important modality to enhance surgical safety while providing the surgeon with updated information to guide their resection. Here the authors review the studies that demonstrate a positive correlation between extent of resection (EOR) and overall survival (OS), although the data is clearer in patients with low-grade gliomas (LGG) and still somewhat controversial in those with higher-grade tumors. We will then review some of the studies that support the role of iMRI and how it has impacted glioma surgery by increasing the EOR. The value of iMRI usage in regards to overall patient outcome can be extrapolated through its effect on EOR. Overall, available data support the safe use of iMRI and as an effective adjunct in glioma surgery.

KEYWORDS:

Extent of resection; high-grade glioma; intraoperative magnetic resonance imaging; low-grade glioma

PMID:
23230537
PMCID:
PMC3514913
DOI:
10.4103/2152-7806.103029
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