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Contemp Clin Dent. 2012 Sep;3(Suppl 2):S240-3. doi: 10.4103/0976-237X.101105.

Role of platelet-rich-fibrin in enhancing palatal wound healing after free graft.

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Department of Periodontics, Bapuji Dental College and Hospital, Davangere, India.


Platelet-rich fibrin has long been used as a wound healing therapy in skin wounds and recently evidence has suggested its usage in oral cavity for different treatment procedures. This article proposes an overview of use of platelet-rich fibrin in management of complicated oral wounds. Excessive hemorrhage of the donor area, necrosis of epithelium, and morbidity associated with donor site have been described as the possible complications after harvesting subepithelial connective tissue graft, but little has been mentioned about their management. The article includes a case report of a 45-year-old male patient who showed a delayed wound healing after subepithelial connective tissue graft harvestation, which was treated with platelet-rich fibrin.


Delayed; palatal; platelet-rich fibrin; subepithelial connective tissue graft; wound healing

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