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Rev Bras Reumatol. 2012 Dec;52(6):968-70.

Increased photosensitivity? Case report of porphyria cutanea tarda associated with systemic lupus erythematosus.

[Article in English, Portuguese]

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Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.


The association of porphyria cutanea tarda (PCT) and systemic lupus erythematosus (SLE) is rare. Systemic lupus erythematosus, of complex pathophysiology and pleomorphic clinical manifestations, is similar to PCT regarding photosensitivity. One finding that can differentiate both diseases is the presence of cutaneous blisters, which are rare in SLE, but characteristic of PCT. We report one case of the association of PCT and SLE and revise the literature, emphasizing pathophysiological, clinical and therapeutic aspects. One relevant information for clinical practice relates to the treatment of SLE with antimalarials, which is a risk for PCT.

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