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Pol Arch Med Wewn. 2012;122 Suppl 1:60-4.

Hypolactasia: a common enzyme deficiency leading to lactose malabsorption and intolerance.

Author information

1
Department of Internal Medicine, University of Tartu and Tartu University Hospital, Tartu, Estonia. margus.lember@kliinikum.ee

Abstract

Adult‑type hypolactasia (lactase nonpersistence or lactase deficiency) is the most common enzyme deficiency leading to lactose intolerance and primary lactose malabsorption. Clinical presentation of the condition includes symptoms resulting from bacterial fermentation of undigested lactose in the colon, which gives rise to gas bloat, increased motility, and loose stools. Diagnosis of the disease is based on clinical symptoms, biochemical, functional, histochemical and genetic tests. Treatment includes dietary restrictions, namely, use of low‑lactose milk, in which lactose has been prehydrolyzed, or non‑lactose milk.

PMID:
23222197
[Indexed for MEDLINE]
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