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Pediatr Emerg Care. 2012 Dec;28(12):1391-5; quiz 1396-8. doi: 10.1097/PEC.0b013e318276fde2.

Ketamine, propofol, and ketofol use for pediatric sedation.

Author information

1
University of Texas Southwestern Medical Center, Dallas, TX 75235, USA.

Abstract

The use of a combination of ketamine and propofol (ketofol) for procedural sedation and analgesia in the emergency department setting shows promise as an agent that may minimize adverse effects of ketamine or propofol as single agents. This article provides a summary of current literature regarding ketofol. It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia.

PMID:
23222112
DOI:
10.1097/PEC.0b013e318276fde2
[Indexed for MEDLINE]

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