Format

Send to

Choose Destination
See comment in PubMed Commons below
Ann Epidemiol. 2013 Feb;23(2):80-6. doi: 10.1016/j.annepidem.2012.11.008. Epub 2012 Dec 5.

Arthritis: its prevalence, risk factors, and association with cardiovascular diseases in the United States, 1999 to 2008.

Author information

1
Lipid Research Group, Heart Research Institute, Sydney, New South Wales, Australia. ongk@hri.org.au

Abstract

OBJECTIVE:

Arthritis is associated with cardiovascular diseases (CVDs). However, there are limited epidemiologic studies on arthritis in a national survey study. We therefore investigated the prevalence of self-reported arthritis and its association with CVDs.

METHODS:

Data from 15,888 subjects aged 40 years or older in the United States National Health and Nutrition Examination Survey 1999 through 2008 were analyzed. CVD was defined as a self-reported history of heart attack, congestive heart failure, coronary heart disease, angina, or stroke.

RESULTS:

The overall prevalence of self-reported arthritis in subjects aged 40 years or older increased from 33.5% in 1999 through 2000 to 37.0% in 2007 through 2008 (P for trend = 0.017). Among subjects with arthritis in 1999 through 2008, 35.3% had osteoarthritis (OA), 17.9% had rheumatoid arthritis (RA), and 10.2% had other types of arthritis, but 36.6% were unaware of their type of arthritis. Compared with subjects without OA, subjects with OA had higher odds for CVDs (odds ratio [OR], 1.53; P < .001), especially angina (OR, 2.18: P < .001). Compared with subjects without RA, subjects with RA had higher odds for CVDs (adjusted OR, 2.39; P < .001), especially congestive heart failure (OR, 3.59; P < .001).

CONCLUSIONS:

Both RA and OA are strongly associated with CVDs in the general population. Further studies are needed to investigate their causal relationship.

PMID:
23218811
DOI:
10.1016/j.annepidem.2012.11.008
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center