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J Am Chem Soc. 2012 Dec 19;134(50):20273-5. doi: 10.1021/ja309908s. Epub 2012 Dec 10.

Artificial, parallel, left-handed DNA helices.

Author information

1
Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.

Abstract

This communication reports an engineered DNA architecture. It contains multiple domains of half-turn-long, standard B-DNA duplexes. While each helical domain is right-handed and its two component strands are antiparallel, the global architecture is left-handed and the two component DNA strands are oriented parallel to each other.

PMID:
23215536
DOI:
10.1021/ja309908s
[Indexed for MEDLINE]

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