Format

Send to

Choose Destination
See comment in PubMed Commons below
J Antibiot (Tokyo). 2013 Feb;66(2):89-95. doi: 10.1038/ja.2012.102. Epub 2012 Dec 5.

New antimicrobial compounds from a marine-derived Bacillus sp.

Author information

1
School of Science and Technology, Bangladesh Open University, Gazipur, Bangladesh.

Erratum in

  • J Antibiot (Tokyo). 2014 Aug;67(8):605-6.

Abstract

In the course of our ongoing research for antimicrobial agents, we isolated five new compounds, three 24-membered macrolactones, macrolactins X-Z (1-3) and two hydroxy unsaturated fatty acids, linieodolides A (5) and B (6), together with a known metabolite, macrolactinic acid (4), from the culture broth of a marine Bacillus sp. The structures of these metabolites were determined on the basis of their spectroscopic data interpretation. Their absolute configurations were addressed by modified Mosher's method and literature data review. Compounds 1-6 showed moderate to potent inhibitory activities (8∼128 μg ml(-1)) against selected pathogenic microorganisms.

PMID:
23211933
DOI:
10.1038/ja.2012.102
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Support Center