Send to

Choose Destination
See comment in PubMed Commons below
J Cerebrovasc Endovasc Neurosurg. 2012 Jun;14(2):79-83. doi: 10.7461/jcen.2012.14.2.79. Epub 2012 Jun 30.

The Comparative Study of Microsurgical Cerebral Aneurysm Clip Implants; Titanium Clip vs. Stainless Steel Clip.

Author information

  • 1Department of Neurosurgery, Gil Hospital, Gachon University, Incheon, Korea.



To perform a comparative study between two groups of populations, titanium (T) group versus stainless steel (S) group, who were clipped with titanium and stainless steel materials, respectively, the incidence of regrowth from the original aneurysms, the clip slippage, and post-clipping seizure attack were analyzed. The patients were followed more than 5 years after microsurgical cerebral aneurysms clipping.


Data from 1986 through 2008 were extensively reviewed on a consecutive series of 3,770 patients who referred for ruptured/unruptured cerebral aneurysms. Forty-seven patients in the S group and 48 in the T group who met inclusion criteria, were selected for this study.


The incidence of regrowth were noted that two out of total 47 patients (4.3%) in the S group, and none in the T group. The clip slippage was not observed in both groups. And there was no statistical difference (p = 0.242) in terms of regrowth between two groups. Seven out of 47 cases (14.9%) developed post-clipping seizure in the S group. On the other hand, two (4.2%) of 48 patients presented the symptom in the T group. Also, there was no significant difference (p = 0.091) between two groups.


The metallic types of clip employed for the microsurgical cerebral aneurysm clipping does not have any significant clinical outcome differences in this study.


Aneurysm; Microsurgical clipping; Stainless steel aneurysmal clip; Titanium aneurysmal clip

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Korean Society of Cerebrovascular Surgeons; Society of Korean Endovascular Neurosurgeons Icon for PubMed Central
    Loading ...
    Support Center