Send to

Choose Destination
See comment in PubMed Commons below
J Bronchology Interv Pulmonol. 2011 Jul;18(3):269-73. doi: 10.1097/LBR.0b013e318222a4f2.

Severe acute fibrinous and organizing pneumonia causing acute respiratory distress syndrome and shock.

Author information

*Division of Pulmonary Medicine and Critical Care Medicine †Department of Medicine ‡Department of Pathology §Division of Pulmonary and Critical Care Medicine, Albert Einstein College of Medicine, Bronx Lebanon Hospital Center, Bronx, NY.


Acute fibrinous and organizing pneumonia (AFOP) is a newly recognized form of diffuse lung injury. The histologic pattern is described as a variant of cryptogenic organizing pneumonia. AFOP is a very rare finding in a human immunodeficiency virus-infected patient. We present a unique case of a 38-year-old human immunodeficiency virus-infected patient admitted with acute respiratory distress syndrome and shock. Flexible bronchoscopy with transbronchial biopsy was consistent with AFOP. He had clinical and radiologic improvement with a course of systemic corticosteroids. This case illustrates that interstitial lung diseases, specifically AFOP, should be included in the differential diagnosis of diffuse lung diseases in patients with respiratory failure with or without shock. Flexible bronchoscopy aids in establishing the diagnosis.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wolters Kluwer
    Loading ...
    Support Center