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Curr Opin Neurobiol. 2013 Apr;23(2):255-60. doi: 10.1016/j.conb.2012.11.005. Epub 2012 Dec 1.

Brain networks underlying episodic memory retrieval.

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1
Center for Vital Longevity and School of Behavioral and Brain Sciences, 1600 Viceroy Drive, Suite 800, Dallas, TX 75235, United States. mrugg@utdallas.edu

Abstract

The importance of the medial temporal lobe to episodic memory has been recognized for decades. Recent human fMRI findings have begun to delineate the functional roles of different MTL regions, most notably the hippocampus, for the retrieval of episodic memories. Importantly, these studies have also identified a network of cortical regions--each interconnected with the MTL--that are also consistently engaged during successful episodic retrieval. Along with the MTL these regions appear to constitute a content-independent network that acts in concert with cortical regions representing the contents of retrieval to support consciously accessible representations of prior experiences.

PMID:
23206590
PMCID:
PMC3594562
DOI:
10.1016/j.conb.2012.11.005
[Indexed for MEDLINE]
Free PMC Article
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