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Trends Immunol. 2013 Apr;34(4):169-73. doi: 10.1016/j.it.2012.10.007. Epub 2012 Dec 1.

B regulatory cells in cancer.

Author information

1
Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK. f.balkwill@qmul.ac.uk

Abstract

B regulatory cells are a newly described subpopulation of B cells that appear to play important roles in autoimmunity and more recently, in cancer. In this review we summarize our current knowledge of B regulatory cells, as well as the body of evidence pointing towards a role for B cells in general, and B regulatory cells in particular, in promoting tumor growth.

PMID:
23206438
DOI:
10.1016/j.it.2012.10.007
[Indexed for MEDLINE]

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