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J Clin Diagn Res. 2012 Oct;6(8):1437-41. doi: 10.7860/JCDR/2012/3408.2382.

Olfactory memory impairment in neurodegenerative diseases.

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Associate Professor, Department of Physiology, Amala Institute of Medical Sciences , Amala Nagar, Thrissur, Kerala-680 555, India.


Olfactory disorders are noted in a majority of neurodegenerative diseases, but they are often misjudged and are rarely rated in the clinical setting. Severe changes in the olfactory tests are observed in Parkinson's disease. Olfactory deficits are an early feature in Alzheimer's disease and they worsen with the disease progression. Alterations in the olfactory function are also noted after severe head injuries, temporal lobe epilepsy, multiple sclerosis, and migraine. The purpose of the present review was to discuss the available scientific knowledge on the olfactory memory and to relate its impairment with neurodegenerative diseases.


Memory; Neurodegenerative diseases; Olfaction

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