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Korean J Ophthalmol. 2012 Dec;26(6):469-72. doi: 10.3341/kjo.2012.26.6.469. Epub 2012 Nov 12.

Anterior ischemic optic neuropathy in a patient with Churg-Strauss syndrome.

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Department of Ophthalmology, Institute for Medicine, Kosin University College of Medicine, Busan, Korea.


We describe a patient with Churg-Strauss syndrome who developed unilateral anterior ischemic optic neuropathy. A 54-year-old man with a history of bronchial asthma, allergic rhinitis, and sinusitis presented with sudden decreased visual acuity in his right eye that had begun 2 weeks previously. The visual acuity of his right eye was 20 / 50. Ophthalmoscopic examination revealed a diffusely swollen right optic disc and splinter hemorrhages at its margin. Goldmann perimetry showed central scotomas in the right eye and fluorescein angiography showed remarkable hyperfluorescence of the right optic nerve head. Marked peripheral eosinphilia, extravascular eosinophils in a bronchial biopsy specimen, and an increased sedimentation rate supported the diagnosis of Churg-Strauss syndrome. Therapy with methylprednisolone corrected the laboratory abnormalities, improved clinical features, and preserved vision, except for the right central visual field defect. Early recognition of this systemic disease by ophthalmologists may help in preventing severe ocular complications.


Churg-Strauss syndrome; Ischemic optic neuropathy; Papilledema

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