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Mol Cell. 2012 Nov 30;48(4):489-90. doi: 10.1016/j.molcel.2012.11.014.

A JARID family demethylase controls differentiation timing through global effects on transcription.

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1
Wellcome Trust Centre for Cell Biology, University of Edinburgh, King's buildings, Mayfield Road, Edinburgh, EH9 3JR, UK.

Abstract

In a recent issue of Developmental Cell, Xu et al. (2012) show that a JARID family H3K4 demethylase delays transcriptional quiescence in yeast to produce robust gametes. Similar mechanisms may alter transcriptional programs in other differentiating cell types.

PMID:
23200122
DOI:
10.1016/j.molcel.2012.11.014
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