Format

Send to

Choose Destination
See comment in PubMed Commons below
Mol Cell. 2012 Nov 30;48(4):487-8. doi: 10.1016/j.molcel.2012.11.007.

Titivated for destruction: the methyl degron.

Author information

1
The University of Texas M.D. Anderson Cancer Center, Science Park-Research Division, P.O. Box 389, Smithville, TX 78957, USA.

Abstract

In this issue, Lee et al. (2012) demonstrate that the degradation of RORα is regulated by the EZH2-DCAF1/DDB1/CUL4 proteasome axis, thus identifying protein methylation as a posttranslational modification that can orchestrate protein destruction through a motif termed the "methyl degron."

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center