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J Ultrasound Med. 2012 Dec;31(12):2025-34.

Sonographically guided cryoneurolysis: preliminary experience and clinical outcomes.

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Department of Radiology and Imaging, Hospital for Special Surgery, New York, New York, USA.


Chronic peripheral nerve pain is a common problem that can arise from numerous causes, for which neurolysis is a therapeutic option. It is postulated that cryotherapy will have less adverse events than other methods of nerve ablation. A retrospective case series review was performed in patients who had undergone sonographically guided cryoneurolysis for Morton neuromas, postsurgical and posttraumatic neuromas, and idiopathic neuralgia. Fifteen of 20 patients had a positive response to cryoneurolysis, as did 2 of 4 patients with borderline symptoms for chronic regional pain syndrome. In view of our positive results, we believe that cryoneurolysis should be considered a reasonable option in performing neurolytic therapy.

[Indexed for MEDLINE]

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