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Nat Rev Immunol. 2013 Jan;13(1):59-66. doi: 10.1038/nri3362. Epub 2012 Nov 30.

The resolution of inflammation.

Author information

1
Rheumatology Research Group at the Centre for Translational Inflammation Research, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham Research Laboratories, Queen Elizabeth Hospital, Birmingham, B15 2WD, UK. c.d.buckley@bham.ac.uk

Abstract

In 2012, Nature Reviews Immunology organized a conference that brought together scientists and clinicians from both academia and industry to discuss one of the most pressing questions in medicine--how do we turn off rampant, undesirable inflammation? There is a growing appreciation that, similarly to the initiation of inflammation, the resolution of inflammation is an intricate and active process. Can we therefore harness the mediators involved in resolution responses to treat patients with chronic inflammatory or autoimmune diseases? Here, we ask five of the speakers from the conference to share their thoughts on this emerging field.

PMID:
23197111
DOI:
10.1038/nri3362
[Indexed for MEDLINE]
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