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Ugeskr Laeger. 2012 Nov 26;174(48):3007-10.

[No evidence of malicious effect of NSAID treatment on bone healing].

[Article in Danish]

Author information

1
An√¶stesiologisk Afdeling, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 K√łbenhavn NV, Denmark. susannejanum@gmail.com

Abstract

The use of NSAIDs for postoperative pain management following orthopaedic surgery or during conservative treatment of fractures is controversial. Experimental animal models suggest NSAIDs inhibit bone healing. In a review of the literature, there was no clinical evidence to support categorical discard of NSAID for postoperative pain relief in uncomplicated cases. However, NSAID should be considered a potentiel risk factor of impaired bone healing and avoided in patients with a high risk of pseudoarthrosis. Recommended daily doses should be respected and duration of treatment should be limited.

PMID:
23195353
[Indexed for MEDLINE]

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