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Clin Sci (Lond). 2013 Mar;124(6):351-70. doi: 10.1042/CS20120378.

Insulin signalling to the kidney in health and disease.

Author information

1
Academic and Children's Renal Unit, University of Bristol, Learning and Research, Southmead Hospital, Bristol BS10 5NB, UK.

Abstract

Ninety-one years ago insulin was discovered, which was one of the most important medical discoveries in the past century, transforming the lives of millions of diabetic patients. Initially insulin was considered only important for rapid control of blood glucose by its action on a restricted number of tissues; however, it has now become clear that this hormone controls an array of cellular processes in many different tissues. The present review will focus on the role of insulin in the kidney in health and disease.

PMID:
23190266
DOI:
10.1042/CS20120378
[Indexed for MEDLINE]

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