No association between overweight and asthma or allergy in adolescence after wheezing in infancy

Acta Paediatr. 2013 Feb;102(2):167-71. doi: 10.1111/apa.12082. Epub 2012 Nov 30.

Abstract

Aims: The aim of the study was to evaluate the association between weight status and asthma, allergy and respiratory symptoms in adolescents with bronchiolitis in infancy.

Subjects and methods: At age 15-18 years, a questionnaire was sent to 96 study subjects hospitalized for wheezing at age <24 months and followed up subsequently. Sixty-seven (70%) of them answered. Weight and height data for body mass index (BMI) calculation were available in 60 (63%) cases. Asthma, allergy, respiratory symptoms and the use of asthma medication were compared between overweight or obese and normal weight groups constructed by age- and sex-specific BMI standard deviation scores (BMI-SDS). Population controls matched for sex, and birth month and place, were recruited for this study phase at age 15-18 years.

Results: Eleven (18.3%) study subjects were overweight (BMI-SDS >0.78 in males and >1.16 in females) and only 3 (5.0%) were obese (BMI-SDS >1.70 in males and >2.10 in females) at 16.5 (median) years of age. Overweight or obesity had no significant association with doctor-diagnosed or self-reported asthma, allergy or the use of inhaled corticosteroids. The negative results were confirmed by adjusted analyses.

Conclusion: Weight status had no association with asthma or allergy in adolescence after wheezing in infancy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Asthmatic Agents / therapeutic use
  • Asthma / drug therapy
  • Asthma / etiology*
  • Body Mass Index
  • Bronchiolitis / complications*
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Health Surveys
  • Humans
  • Hypersensitivity, Immediate / etiology
  • Infant
  • Logistic Models
  • Male
  • Obesity / complications
  • Overweight / complications*
  • Respiratory Sounds*
  • Risk Factors
  • Surveys and Questionnaires

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents