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Ulus Travma Acil Cerrahi Derg. 2012 Sep;18(5):411-6. doi: 10.5505/tjtes.2012.76736.

[The role of blood S100B and lactate levels in minor head traumas in children and adults and correlation with brain computerized tomography].

[Article in Turkish]

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  • 1Department of Emergency Medicine, Ankara Training and Research Hospital, Ankara, Turkey.



In this study, we aimed to set levels of blood S100B and lactate and to determine any correlation with brain computerized tomography in minor head traumas in children and adults.


This clinical trial is a prospective study including 100 head trauma patients who applied to Ankara Training and Research Hospital emergency service.


In this study, cut-off ranges of 0.0-0.15 ug/ml and 0.9-1.7 mmol/L for blood S100B and lactate levels, respectively, were used. S100B level was higher than the cut-off range in 42% of patients and lactate level was higher in 56% of patients. No significant differences were determined between age groups. When the relation between S100B and lactate levels with brain CT was evaluated, no statistically significant relation was determined.


According to our results, in minor head traumas, the determination of elevated serum S100B and lactate levels cannot take the place of clinical examination and the use of cranial CT. Although the patients in our study group had minor head trauma, we do not consider S100B and lactate to be reliable markers for estimating progression.

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