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J Magn Reson Imaging. 2013 Jul;38(1):168-72. doi: 10.1002/jmri.23951. Epub 2012 Nov 27.

Assessment of perfusion in normal carpal bones with dynamic gadolinium-enhanced MRI at 3 Tesla.

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1
Department of Radiology, Lund University, Malmö, Sweden. gunilla.muller@med.lu.se

Abstract

PURPOSE:

To investigate the normal enhancement patterns of the scaphoid, lunate, and capitate bones with dynamic contrast-enhanced magnetic resonance imaging (MRI).

MATERIALS AND METHODS:

The study was approved by the hospital's Ethics Committee. Nineteen volunteers (13 female, 6 male; mean age 38 years) were examined and all gave written consent. Perfusion was assessed at 3 Tesla using dynamic contrast-enhanced MRI. After two-dimensional (2D) motion correction of the data set, regions of interest were placed in the capitate, lunate, and distal and proximal pole of scaphoid bone and from the mean signal intensities (SI), the enhancement was computed. The four locations were compared for time to peak, delay time, maximum enhancement, and maximum slope using Friedman's two-way analysis of variance.

RESULTS:

Typical SI versus time curves revealed two components: a faster component with strong contrast enhancement and a slow component with prolonged enhancement. The mean value (standard deviation, SD) for maximum enhancement was 51 (33)% in the capitate, 54 (25)% in the lunate, 51 (34)% in the proximal pole and 51 (28)% in the distal pole of the scaphoid. The result of the Friedman test showed no significant difference (P < 0.05) in the perfusion variables between the capitate, lunate, and distal and proximal scaphoid bones.

CONCLUSION:

Assessment of perfusion in normal carpal bone using contrast-enhanced MRI is possible. Optimization of the method and understanding of the normal perfusion may allow evaluation of pathological conditions such as osteonecrosis.

KEYWORDS:

carpal bones; contrast-enhancement; magnetic resonance imaging; perfusion

PMID:
23188589
DOI:
10.1002/jmri.23951
[Indexed for MEDLINE]
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