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J Acquir Immune Defic Syndr. 2013 Mar 1;62(3):322-328.

Rates and cost of hospitalization before and after initiation of antiretroviral therapy in urban and rural settings in South Africa.

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  • 1Center for Global Health and Development, Boston University, Boston, MA, USA. gesine@bu.edu

Abstract

Few studies have compared hospitalizations before and after antiretroviral therapy (ART) initiation in the same patients. We analyzed the cost of hospitalizations among 3906 adult patients in 2 South African hospitals, 30% of whom initiated ART. Hospitalizations were 50% and 40% more frequent and 1.5 and 2.6 times more costly at a CD4 cell count, 100 cells/mm(3) when compared with 200–350 cells/mm(3) in the pre-ART and ART period, respectively. Mean inpatient cost per patient year was USD 117 (95%confidence interval, 85 to 158) for patients on ART and USD 72(95% confidence interval, 56 to 89) for pre-ART patients. Raising ART eligibility thresholds could avoid the high cost of hospitalization before and immediately after ART initiation.

PMID:
23187948
PMCID:
PMC3625673
DOI:
10.1097/QAI.0b013e31827e8785
[PubMed - indexed for MEDLINE]
Free PMC Article
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