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Endocr Pract. 2013 Jan-Feb;19(1):e21-3. doi: 10.4158/EP12241.CR.

Cola-induced hypokalemia-a case report and review of the literature.

Author information

1
Department of Endocrinology, SUNY-Downstate Medical Center, Brooklyn, NY 11209, USA.

Abstract

OBJECTIVE:

We aim to describe an unusual and underappreciated cause for hypokalemia.

METHODS:

We describe a patient diagnosed with cola-induced hypokalemia and review the literature.

RESULTS:

Ingestion of massive amounts of cola can lead to severe hypokalemia through several pathophysiologic mechanisms. These perturbations include osmotic diarrhea, osmotic diuresis, and hyperinsulinemia secondary to hyperglycemia with resultant intracellular to cellular shifts in potassium. These effects are magnified by concomitant high levels of caffeine.

CONCLUSION:

Ingestion of large quantities of cola should be added to differential diagnosis for severe hypokalemia.

PMID:
23186978
DOI:
10.4158/EP12241.CR
[Indexed for MEDLINE]

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