Format

Send to

Choose Destination
Adv Healthc Mater. 2013 May;2(5):678-81. doi: 10.1002/adhm.201200342. Epub 2012 Nov 26.

Simvastatin-loaded β-TCP drug delivery system induces bone formation and prevents rhabdomyolysis in OVX mice.

Author information

1
University of Technology Sydney, School of Medical and Molecular Sciences, Ultimo, Sydney, NSW, 2007, Australia. Joshua.chou@uts.edu.au

Abstract

Bone formation and regeneration is a prolonged process that requires a slow drug release system to assist in the long-term recovery. A drug-delivery system is developed that allows for the controlled release of simvastin, without exhibiting the side effects associated with high concentrations of simvastatin, and is still capable of inducing constant bone formation.

PMID:
23184712
DOI:
10.1002/adhm.201200342
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center