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Cell Res. 2013 Mar;23(3):314-6. doi: 10.1038/cr.2012.163. Epub 2012 Nov 27.

Beating in a dish: new hopes for cardiomyocyte regeneration.

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1
Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Abstract

Functional human cardiomyocytes hold great promise in cell transplantation-based therapy to treat many heart diseases. To meet this devastating and clinical need, researchers are infatuated with developing novel technologies and methodologies to efficiently generate cardiomyocytes through either stem cell differentiation or cell lineage transdifferentiation. Though exciting progress has been made, challenges remain to be addressed before the translation from bench side to bed side can be fulfilled.

PMID:
23184058
PMCID:
PMC3587704
DOI:
10.1038/cr.2012.163
[Indexed for MEDLINE]
Free PMC Article
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