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Obstet Gynecol Clin North Am. 2012 Dec;39(4):479-93. doi: 10.1016/j.ogc.2012.09.002.

Obesity and reproductive function.

Author information

1
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, MO 63108, USA. jungheime@wustl.edu

Abstract

Obesity is associated with multiple adverse reproductive outcomes, but the mechanisms involved are largely unknown. Obesity has been referred to as a "complex system," defined as a system of heterogeneous parts interacting in nonlinear ways to influence the behavior of the parts as a whole. Human reproduction is also a complex system; hence the difficulty in identifying the mechanisms linking obesity and adverse reproductive function. This review discusses the adverse reproductive outcomes associated with obesity and the mechanisms involved and concludes with a discussion of public health policy with respect to the treatment of infertility in obese women.

PMID:
23182555
PMCID:
PMC3520133
DOI:
10.1016/j.ogc.2012.09.002
[Indexed for MEDLINE]
Free PMC Article

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