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Curr Opin Cell Biol. 2012 Dec;24(6):833-7. doi: 10.1016/ Epub 2012 Nov 22.

Global control of cell growth in fission yeast and its coordination with the cell cycle.

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Cell Cycle Lab, Cancer Research UK, London Research Institute. 44 Lincoln's Inn Fields, London, WC2A 3LY, UK.


Cell growth is a fundamental process for every cell but its pleiotropic complexity makes it difficult to comprehend. Global aspects of cellular growth, like the overall determinants of growth rate are not well understood. Here we examine the cell growth pattern of the fission yeast Schizosaccharomyces pombe during the mitotic and meiotic cell cycles. We also explore recent findings illuminating aspects of cell size homeostasis and cell growth regulation, and propose that there are global controls over growth acting at the level of the cell.

[Indexed for MEDLINE]

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