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MAGMA. 2013 Feb;26(1):99-113. doi: 10.1007/s10334-012-0353-4. Epub 2012 Nov 21.

MRI for attenuation correction in PET: methods and challenges.

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1
Central Institute for Electronics, Forschungszentrum Jülich, 52425 Jülich, Germany. g.wagenknecht@fz-juelich.de

Abstract

In current combined PET/MR systems, PET attenuation correction is based on MRI, since the small bore inside MRI systems and the strong magnetic field do not permit a rotating PET transmission source or a CT device to be integrated. Unlike CT measurements in PET/CT scanners, the MR signal is not directly correlated to tissue density and thus cannot be converted by a simple transformation of intensity values. Various approaches have been developed based on templates, atlas information, direct segmentation of T1-weighted MR images, or segmentation of images from special MR sequences. The advantages and disadvantages of these approaches as well as additional challenges will be discussed in this review.

PMID:
23179594
PMCID:
PMC3572388
DOI:
10.1007/s10334-012-0353-4
[Indexed for MEDLINE]
Free PMC Article
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