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Clin Oral Implants Res. 2013 Apr;24(4):363-71. doi: 10.1111/clr.12067. Epub 2012 Nov 26.

Experimental periodontitis and peri-implantitis in dogs.

Author information

1
Department of Periodontology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

Abstract

AIM:

To analyze the tissue reactions following ligature removal in experimental periodontitis and peri-implantitis in dogs.

MATERIAL AND METHODS:

Four implants with similar geometry and with two different surface characteristics (turned/TiUnite Nobel BioCare AB, Göteborg) were placed pair-wise in a randomized order in the right side of the mandible 3 months after tooth extraction in 5 dogs. Experimental peri-implantitis and periodontitis were initiated 3 months later by ligature placement around implants and mandibular premolars and plaque formation. The ligatures were removed after 10 weeks, and block biopsies were obtained and prepared for histological analysis 6 months later.

RESULTS:

It was demonstrated that the amount of bone loss that occurred during the period following ligature removal was significantly larger at implants with a modified surface than at implants with a turned surface and at teeth. The histological analysis revealed that peri-implantitis sites exhibited inflammatory cell infiltrates that were larger, extended closer to the bone crest and contained larger proportions of neutrophil granulocytes and osteoclasts than in periodontitis.

CONCLUSION:

It is suggested that lesions produced in experimental periodontitis, and peri-implantitis are different and that implant surface characteristics influence the inflammatory process in experimental peri-implantitis and the magnitude of the resulting tissue destruction.

PMID:
23176551
DOI:
10.1111/clr.12067
[Indexed for MEDLINE]

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